Use of certain antidepressants during the first three months of pregnancy may cause a slightly increased risk of giving birth to babies with heart defects. The 4th Tenor video Sweet and Lowdown dvdrip
Danish researchers found that septal heart defects, or malformations in the wall separating the right side of the heart from the left, were more common in women taking antidepressants in their first trimester. While some of these heart defects resolve on their own, others require surgery.
The risks were seen in a class of medications known as selective serotonin reuptake inhibitors (SSRI), such as sertraline (Zoloft and Lustral) and citalopram (Celexa). Women who took more than one SSRI early in their pregnancy had a risk four times higher than those who didn’t. However, this risk is relatively low: 246 women would have to take such medication in order to see one septal heart defect, and 62 mothers would have to take more than one SSRI to see a problem in one child.
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Many experts agree that the absolute risk is low, and this must be balanced against the potential substantial risk of under- or untreated depression during pregnancy.
"The concern with pregnant women with depression, if you take them off their medication, they can have a relapse into severe depression and this could lead to self-destructive behaviors," said Jennifer Wu, an obstetrician and gynecologist at Lenox Hill Hospital in New York City.
Previous studies have found that pregnant women who stopped taking their antidepressant medications were five times more likely to relapse than women who continued with the medication.
